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Thread: Herpes Simplex

  1. #21
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    HSV-1 and HSV-2 In Asia

    Asia

    [edit] Eastern and South East Asia

    HSV-1 seroprevalence in some Asian countries is low, relative to other countries worldwide, with only 51% women in Thailand, and between 50-60% in Japan possessing antibodies.[3][5] HSV-2 seroprevalence in developing Asian countries is comparable (10-30%) to that observed in North America and Northern Europe.[24] However, estimates of HSV-2 infectivity in Thailand are higher than observed in other Eastern Asian countries; total HSV-2 seroprevalence is approximately 37% in this country.[5] HSV-2 seroprevalence is low in women in the Philippines (9%), although commencing activity while young is associated with an increase risk of acquiring HSV-2 infection; woman starting sexual activity by the time they reach 17 are seven times more likely to be HSV-2 seropositive than those starting sexual activity when over 21.[27] In South Korea, incidence of HSV-2 infection in those under the age of 20 is low, only 2.7% in men and 3.0% in women.[6] Seroprevalence levels increase in older South Koreans however, such that the population over 20 that has antibodies against HSV-2 is 21.7% of men and 28% of women.[6]

    [edit] Southern Asia

    In India 33.3% of individuals are seropositive for HSV-1 and 16.6% are seropositive for HSV-2. Those with both HSV-1 and HSV-2 antibodies are estimated at 13.3% of the population. Indian men are more likely to be infected with HSV-2 than women, and increasing seroprevalence of this virus is associated with an increasing age.[28]








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  2. #22
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    Genital Herpes Symptoms

    By Amanda Chan



    updated 4/12/2011 5:20:55 PM ET
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    Even people who don't show symptoms of genital herpes can harbor active forms of the virus that can be spread to sexual partners, according to a new study.

    People who are infected with the herpes simplex virus type 2, but don't have symptoms, still have active forms of the virus detected on their genital tract 10 percent of the time, the study said.






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    And people who do have symptoms of herpes infection carry active forms of the virus on their genital tract 20 percent of the time, said study researcher Dr. Christine Johnston, acting assistant professor of medicine at the University of Washington.

    It's long been known that the herpes simplex virus type 2 is contagious even if a person doesn’t have symptoms of the virus, Johnston said. But the new finding shows what percent of the time the virus is actually active and infectious, she added.

    "These findings will help us counsel patients who are diagnosed with [herpes simplex virus type 2] infection about their risks of transmission to others, which is often a key concern for people diagnosed with genital herpes," Johnston told MyHealthNewsDaily.

    Herpes simplex virus type 2 is sexually transmitted and causes most cases of genital herpes, which manifests as blisters that form on the genitals and rectum, according to the Centers for Disease Control and Prevention.

    Herpes simplex virus type 1 can also cause genital herpes, but typically this form of the virus only causes cold sores in or around the mouth.


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    .
    The study will be published April 13 in the Journal of the American Medical Association.

    Viral shedding
    Johnston and her colleagues compared the rates of viral shedding, the rate at which the virus replicates and is therefore considered contagious, in 498 people with genital herpes between 1992 and 1998.

    Researchers had each participant collect a swab of genital secretions once a day for at least 30 days, the study said.

    People with symptoms of genital herpes had more episodes of viral shedding over a year (17.9 episodes), than those without symptoms (12.5 episodes), the study said.

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    However, these results show that even people without symptoms of herpes are still contagious and may not realize they are passing the virus on to their sexual partners, Johnston said.

    What's at stake
    Transmission of herpes occurs through direct person-to-person contact with an area of the body that is shedding the virus, she said.

    "We do not know if there is a threshold quantity of virus above which people are contagious," she said, but "we presume that if people are shedding virus, they are at risk of transmitting virus."

    More than 16 percent of people ages 14 to 49 in the United States are infected with the herpes simplex virus type 2, according to the CDC.

    There is no cure for herpes, but the study highlights the need for vigilant prevention of the virus, Johnston said.

    Prevention strategies include using condoms, suppressive antiviral therapy and disclosure of having herpes to sexual partners. Each of these strategies is 50 percent effective in reducing the risk of genital herpes transmission, Johnston said.

    Pass it on: People infected with genital herpes but don't show any symptoms can still be contagious and spread the virus to sexual partners.
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    Last edited by Meteor; 07-12-2012 at 08:54 PM.

  3. #23
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    How long do I have to wait before a herpes blood test is effective?

    Question: How long do I have to wait before a herpes blood test is effective?

    Although most people who will become symptomatic with genital herpes start showing symptoms within two weeks of exposure to the virus, the vast majority of people with herpes will never have symptoms at all. That doesn't mean that they can't still transmit the genital herpes virus.
    Even if herpes tests aren't perfect, they are often the only way to know if you are infected. The problem is that many herpes blood tests look for antibodies to the virus - and those are not produced right away. The question is this: How long should you wait before you can be reasonably certain a genital herpes blood test will be effective?

    Answer: In the presence of symptoms, it is easy for a doctor to diagnose a herpes infection - either by simply examining the outbreak or by swabbing the sores for the herpes virus. However, in order to determine if someone is sub-clinically infected - in other words, if they have an infection but no obvious symptoms - doctors need to do a blood test.
    Blood tests for HSV-2, the virus that usually causes genital herpes, generally look for the presence of antibodies to the virus rather than the virus itself. Unfortunately, it takes some time for the body to mount a detectable antibody response after infection. That's why you can't simply go get tested the day after you've been exposed to genital herpes to find out if you have the disease - even if you were infected, at that point there's no way for the test to pick it up. So, how long does it take for a genital herpes blood test to become positive after exposure? The answer is that it depends on the test.

    Various studies have investigated how long it takes from when genital herpes symptoms show up to when an individual tests positive on a blood test for HSV-2. As it turns out, the range varies a great deal, both between studies and between tests. For example the median time from symptoms to a positive HSV-2 blood test was:
    •HerpeSelect ELISA - 21 days for people who were HSV-1 negative and 23 days for people who were HSV-1 positive. (Ashley-Morrow et al. 2003)
    •Western Blot - 40 days for people who were HSV-1 negative and 47 days for those who were HSV-1 positive. (Ashley-Morrow et al. 2003)
    •Western Blot - 68 days. (Morrow et al. 2003)
    •Kalon ELISA - 120 days. (Morrow et al 2003)
    •Focus ELISA - 21 days. (Morrow et al 2003)

    In other words, since it usually takes around 2 weeks for symptoms to show up, it's probably a good idea to wait at least a month or two before even considering getting an HSV-2 test after a potential exposure -- and you might want to consider getting retested after six months. Remember, after all, that those are only median times and that they were highly variable. Some infected people will seroconvert quickly, while others will take even longer before a herpes blood test accurately shows them to be positive.

    Note: There is no practical way for researchers to directly answer the question of how long it takes for a positive test to show up in asymptomatic people, since you'd have to know both that they had been infected and when they had become infected. If a person is asymptomatic, neither piece of information is available -- since there is no way to tell they are infected until they test positive. The assumption is that the time course to a positive genital herpes blood test is similar to that seen in symptomatic individuals, although that assumption is difficult to verify since most asymptomatic individuals who eventually test positive do not know exactly when they were exposed.

    Sources:

    Ashley-Morrow R, Krantz E, Wald A. Time course of seroconversion by HerpeSelect ELISA after acquisition of genital herpes simplex virus type 1 (HSV-1) or HSV-2. Sex Transm Dis. 2003 Apr;30(4):310-4.

    Morrow RA, Friedrich D, Krantz E. Performance of the focus and Kalon enzyme-linked immunosorbent assays for antibodies to herpes simplex virus type 2 glycoprotein G in culture-documented cases of genital herpes. J Clin Microbiol. 2003 Nov;41(11):5212-4.

    The CDC Genital Herpes Fact Sheet.











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    Last edited by Meteor; 07-12-2012 at 08:54 PM.

  4. #24
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    Recommended Doctors For Checkups

    Where to find us

    Dr. Tan & Partners @ Robertson


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  5. #25
    this is a good info
    UbErZoNe

  6. #26
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    Tks for sharing

  7. #27
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    Spent me one week to get all these information.
    You guys are old bird, there are alot for me to learn from you both.

 

 

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